1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid 3,7,11-trimethyl-2,6,10-dodecatrienyl ester

Name	indomethacin farnesil
Synonyms	IM-F Infree E-0710 Infree S indomethacin farnesil 3,7,11-TriMethyldodeca-2,6,10-trien-1-yl 2-(1-(4-chlorobenzoyl)-5-Methoxy-2-Methyl-1H-indol-3-yl)acetate 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid 3,7,11-trimethyl-2,6,10-dodecatrienyl ester
CAS	85801-02-1

Molecular Formula	C34H40ClNO4
Molar Mass	562.14
Water Solubility	Insoluble in water
Appearance	clear liquid
Color	Light yellow to Yellow to Orange
Storage Condition	Sealed in dry,Room Temperature
Physical and Chemical Properties	Acute toxicity LD50 mice, rats, dogs (mg/kg):6800~7800,1680~2000,>3000 oral.

RTECS

NL3522820

use	new non-steroidal anti-inflammatory painkillers can be well distributed in inflammatory tissues. It is suitable for rheumatoid arthritis, osteoarthritis, low back pain, periarthritis of humerus and neck, shoulder and arm syndrome.
Production method	12g indomethacin is chlorinated with dichlorosulfoxide to obtain its acid chloride compound. The acid chloride compound and 7.6 g3,7, 1l-trimethyl-2,6, 10-dodecartrienol were reacted at room temperature for 1h in the presence of triethylamine in a solution of tetrahydrofuran. 14g of indomethacin fadryl ester was obtained.

Last Update：2024-04-09 21:00:56

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CAS: 85801-02-1
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Mobile: 18021002903
QQ: 3008007409

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1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid 3,7,11-trimethyl-2,6,10-dodecatrienyl ester Request for Quotation